Platelet rich plasma in dermatology and aesthetic medicine

Usage of platelet rich plasma (PRP) in aesthetic medicine is a new concept. In dermatology and cosmetic medicine, PRP has been used to treat acne, scarring, and alopecia (especially in women). It is also effective for skin rejuvenation and tightening around the eyes. Before injecting PRP to treat hair loss, a tiny scalp roller with spikes is used to stimulate the thinning areas. The rationale is that this sends a message to the hair follicles to start the healing process. Then, PRP is injected over the affected area to further stimulate stem cells in the follicle. Platelet-rich plasma is injected by multiple tiny punctures under the dermis, with or without topical local anesthesia [1,2]. The process is painless if sufficient topical anesthesia is applied. When PRP is injected into the damaged area, it stimulates the tissue, causing mild inflammation that triggers the healing cascade. As a result, new collagen begins to develop. As this collagen matures, it begins to shrink and tightens and strengthens the skin. Improvement in skin texture and tone is noticeable within 3 weeks. Full collagen regeneration requires 3 months [3,4]. The PRP treatments can be used on all skin types and tones. Minimal swelling, bruising, and redness for the initial 12 to 24 hours are expected. A bruise at the needlestick site may be visible for 2 to 3 days. Swelling from the fluid is what the patient will notice first. During several weeks, the platelets stimulate growth factors, which assists in more collagen stimulation. Treatment results vary but last up to 18 months in most patients.